sulfonylurea and glp 1 JCI Drugs for Diabetes Mellitus

The insulin-dependent mechanism of action of canagliflozin offers a unique benefit profile in patients with type 1 diabetes, which is different from that of standard insulin therapies that are associated with hypoglycemia and weight gain, the researchers wrote

Health professionals generally advise against this diet due to the associated risks and lack of scientific evidence

10.1016/j.bone.2012.11.039 75 GaultV

The results reported in the company-sponsored comparative study represent participant-reported outcomes and do not guarantee that any individual will achieve similar results

Comorbidities such as cardiovascular disease, sleep apnea, or uncontrolled diabetes change priorities: reduce hypoglycemia risk, avoid volume depletion, and maintain glycemic targets that fit the procedures risk profile

So for people with diabetes, insulin is not able to do its job