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Key Takeaways Effectiveness: Tirzepatide may lead to greater average weight loss in trial populations
Standard escalation: Weeks 1 to 4: 2.5 mg Weeks 5 to 8: 5 mg Weeks 9 to 12: 7.5 mg Weeks 13 to 16: 10 mg Weeks 17 to 20: 12.5 mg (optional) Weeks 21+: 15 mg (optional) Stop escalating when: Weight loss velocity is 0.5% to 1% of body weight per week Side effects become moderate or worse Patient reaches personal weight goal Step 5: Assess response at week 12 to 16

Although lack of insurance coverage and cost were barriers for about half of respondents interested in taking GLP-1s, another 36 per cent said they would take the medication if the risk of side-effects was lower

Calcium is another essential mineral that supports bone health, but you probably already knew that

Int J Mol Sci (2022) 23(2):739

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