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Another metaanalysis confirmed this finding in data based on GLP1 receptor agonist therapy and cardiovascular outcome, including 55,921 patients (Abd El Aziz et al., 2020), as well as studies comparing the risk of pancreatitis (Azoulay et al., 2016a) or pancreatic cancer (Azoulay et al., 2016b) between GLP1 receptor agonists and other antidiabetic medications

Injectables, such as retatrutide, CagriSema (cagrilintide and semaglutide), and MariTide (maridebart cafraglutide), are in more advanced clinical trials

In 2005, the first GLP-1 agonist, exenatide, was approved for the management of Type 2 diabetes mellitus (T2DM) [6]

[DOI] [PubMed] [Google Scholar] 52.Salcedo I., Tweedie D., Li Y., Greig N.H

But in humans it can be used to suppress our pain pathway