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Limitations and strengths This study is based on comprehensive longitudinal data from multiple nationwide registries in Denmark, where information can be linked across registries due to the unique personal identification number

Abstract Background

The American Academy of Pediatrics and major obstetric societies suggest delaying GLP-1 initiation or considering alternatives during active breastfeeding

Multiomics, miRNAs, gene-editing technologies and epigenetic targets have received considerable attention but have yet to deliver usable therapies

Therefore, maintaining the integrity of the intestinal barrier has a comprehensive impact on human health, so several studies have been conducted to understand the mechanisms involved in improving the integrity of the gut barrier

GLP-1RAs and Other Mechanisms According to the Global Burden of Disease 2019 data report, 68 although age-standardized mortality from chronic respiratory diseases has shown a gradual decline globally from 1990 to 2019, COPD still has the highest age-standardized mortality rate of all chronic respiratory diseases and COPD is also the largest burden of death from chronic respiratory diseases, a situation that may remain difficult to improve in the future