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We also know that adherence to GLP-1s can be challenging due to their adverse effect profile

The effects run almost equally in both directions which tells you this is not a simple story

this is a weekly injection through a pen that must be kept refrigerated

Apoptosis and its Role in Parkinsons Disease

Similar to other GLP1RAs, dulaglutide has shown quite rapid and sustained weight loss of 1.5-3 kg, contrasting with a weight increase with other GLP1RAs

13 , 15 Although the magnitude of this effect in clinical settings remains unclear, there is a biological rationale to consider an elevated risk of volume-related symptoms in susceptible individuals, such as older adults, those with orthostatic hypotension, or patients on multidrug antihypertensive regimens