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Regulatory submission for retatrutide is expected in 2026

Although rare, associations with nonarteritic anterior ischemic optic neuropathy, pancreatitis, medullary thyroid carcinoma, and acute kidney injury (AKI) have been reported, primarily through pharmacovigilance and case-based evidence

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In a statement published on 6 June 2025, the PRAC said it had reviewed all available data on []

We show that the GLP-1R is highly expressed within the LS