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To qualify for Wegovy, youll typically need one of the following: A BMI of 30 or higher (classified as obesity ), or A BMI of 27 or higher with at least one weight-related health condition Weight-related conditions may include: High blood pressure (hypertension) High cholesterol (dyslipidemia) Type 2 diabetes Heart disease Obstructive sleep apnea Polycystic ovary syndrome ( PCOS ) In addition, in March 2024 the FDA expanded Wegovys approval to include reducing the risk of major cardiovascular events like heart attac k, stroke, and cardiovascular death in adults with cardiovascular disease plus overweight or obesity

Personalized plans that take into account genetic background might allow some individuals to keep the weight off in the long term

Semaglutide (Ozempic, Wegovy, Rybelsus) by Novo Nordisk is the established standard of care, with FDA approval since 2017, proven cardiovascular benefit, and availability in both injectable and oral formulations

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Poor sleep is associated with insulin resistance, increased hunger, and weight gain, which might reduce some benefits of GLP-1s [175]