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HKY conceived and designed the study, supervised the experiments, interpreted the data, and was responsible for drafting and revising the manuscript for important intellectual content

[16] showed significant, dose-dependent reductions in body weight, BMI and waist circumference, especially with higher doses (8 mg and 12 mg)

The most complex protocol in the world is worthless if adherence falls apart

Consensus thresholds 67 % agreement (scores 7 by 10/15 experts) were defined a priori during the planning phase and communicated to panellists before the first round of voting

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However, individual responses can vary significantly, so continuous monitoring for any new or intensified side effects is always advised