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This initiates a cascade that leads to the activation of protein kinase A (PKA), closing of potassium channels, depolarization, and release of calcium from the endoplasmic reticulum.3 An increase of intracellular calcium levels within the cell initiates insulin expression in the nucleus, stimulates energy (ATP) production in the mitochondria, and triggers the release of insulin into the blood stream in a glucose dependent manner (image adapted from Adipogen Life Sciences).4,5 Several commercially and prescribed agents are now available for the management of obesity and type 2 diabetes

Plus, not everyone wants to go the prescription route

Incorporate stress management techniques, such as meditation, yoga, or deep breathing exercises into your daily routine

Originally developed to treat type 2 diabetes, this dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist is proving to be a game-changer in improving insulin sensitivity

In addition to my weekly essay this week, I needed a space to make sense of the disgusting display of shameless corporatized slop that unfortunately oozed its way onto my T.V

Demand had so thoroughly outpaced manufacturing capacity that continuity of care for people with type 2 diabetes was at risk and prescribers were urged not to initiate GLP-1 therapies outside their approved indications while constraints remained in place