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What the Latest Clinical Trial Results Show According to publicly reported late-stage trial data: Participants receiving higher doses achieved average weight loss approaching 2530% over approximately 68 weeks Some individuals lost more than 70 pounds during the study period Participants with obesity and knee osteoarthritis also reported significant reductions in joint pain These outcomes exceeded the average weight loss typically reported in clinical trials of currently approved GLP-1 medications

Prior studies have suggested a benefit of GLP-1 RAs for Hidradenitis Suppurativa (HS)

Tirzepatide, the active ingredient in Mounjaro, is FDA-approved for chronic weight management under the brand name Zepbound

randomized trials and meta-analyses provide preliminary evidence of reduced clinical deterioration in some outpatient COVID-19 populations, although results are heterogeneous and not sufficient to alter standard infectious disease practice beyond investigational contexts [42]