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Description
It typically begins 2 to 4 months after the onset of rapid weight loss and resolves within 6 to 12 months
In Eli Lillys landmark SURMOUNT-1 clinical trial published in the New England Journal of Medicine , participants on the highest weekly dose (15 mg) achieved an average body weight reduction of 22.5% (approximately 52 lbs) over 72 weeks , compared to a mere 2.4% in the placebo group [1]
Always use a calculator to verify your doses, especially with compounded formulations
Which GLP-1 is the most effective for weight loss
What this means for your dosing protocol If you are currently on compound tirzepatide, the regulatory uncertainty creates practical concerns
The two you want to look for are the drug list (also called a formulary, pharmacy benefits document, or PDL) and the summary of benefits
