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The unique pancreas of an ugly fish helped accelerate a revolution in modern medicine.

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Endocr Rev 42(2):101132 McLean BA, Wong CK, Kaur KD, Seeley RJ, Drucker DJ (2021) Differential importance of endothelial and hematopoietic cell GLP-1Rs for cardiometabolic versus hepatic actions of semaglutide

4 Highest concentrations of released GLP-1 are found immediately within the hepato-portal circulation since GLP-1 is quickly metabolized to GLP-1 (936)amide by dipeptidyl-peptidase-IV (DPP-IV)

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