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J Neurosci Res (2003) 72(5):60312

The study, published in the scientific journal Science Advances , provides strong evidence that a genetically determined form of hyperhidrosis arises from overstimulation of the nerves that control the sweat glands

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A., Katsiki N., Blundell J., Fruhbeck G., Kiortsis D

Whats more, a recent retrospective, multicenter cohort study denied higher occurrence of nonarteritic anterior ischemic optic neuropathy (NAION) in GLP-1RAs users and suggested that its potential benefits for blood glucose control and cardiovascular health likely outweigh its risks (Chou et al., 2025), despite that a few research have reported association between semaglutide prescription and a higher risk of NAION(61)

Adding multi-day fasting to pharmacological appetite suppression creates risk of hypoglycemia, severe electrolyte imbalance, excessive muscle breakdown, nutrient deficiency, and in people with type 2 diabetes, dangerous metabolic instability