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The medication works through appetite centers in the brain and pancreatic hormones, not through the intestinal wall
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19,20 From the current recommendation, pioglitazone has been established in both diabetic and nondiabetic MAFLD patients with significant fibrosis (F2), whereas vitamin E is recommended in nondiabetic MAFLD patients with F2 non-cirrhosis
[DOI] [PMC free article] [PubMed] [Google Scholar] 41.De Leon A., Roemmich J., Casperson S
doi:10.1186/s13028-019-0480-2 79
