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Importantly, in patients receiving GLP-1/GIP (and emerging multi-agonist) therapies with substantial weight loss, creatinine-based eGFR equations may overestimate kidney function due to reductions in muscle mass and creatinine generation

Genetic context complementsrather than replacesmedical evaluation and provider judgment

Working with an obesity medicine specialist, he says, is ideal, though he acknowledges finding one may be a challenge

The increased prevalence indicates the need for novel therapeutic strategies and supportive care to manage the symptoms of these neurodegenerative diseases and to improve the quality of life for the affected individuals

Drugs like Zepbound, Wegovy, and Ozempic are commanding headlines, reshaping public expectations, and driving record-breaking demand

And it is partly the absence of sufficient resistance training in most study populations