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It was produced primarily in enteroendocrine L-cells and released together with GLP-1 in response to food intake

Data from three groups or more were assessed by an ordinary one-way ANOVA test followed by Bonferroni post hoc analysis

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Short-acting RAs, such as exenatide (Byetta), lixisenatide and beinaglutide, have a duration of action of only a few hours after being subcutaneously injected., thus need multiple times injection daily

For daily prevention of GLP-1 constipation, 400 milligrams of magnesium oxide taken at bedtime is the standard recommendation from gastroenterologists