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Obes Rev 2025;26:e13929

Your healthcare team can interpret these results in the context of your overall health and adjust treatment strategies accordingly, ensuring that both diabetes management and cardiovascular risk reduction are optimally addressed through evidence-based approaches aligned with current UK clinical guidelines

These changes reflect semaglutide's effects on appetite regulation centers in your brain

Interestingly, this effect seems to be mediated through hepatic glucagon signalling, as infusion into the portal vein induced a satiating response whereas infusion into the inferior vena cava did not (64)
