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In conclusion, although GLP-1s alone can produce significant weight reduction and related health benefits, several challenges limit its long-term success for individuals and populations
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Br J Pharmacol 155(7):10851092 Guan Q (2019) A comprehensive review and update on the pathogenesis of inflammatory bowel disease

Dropout and adverse event analysis As most of the included studies only reported dropout rates and the incidence of adverse events at the endpoint, we were unable to establish a time-course model for them

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And here, the targets couldn't be more different
