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[DOI] [PubMed] [Google Scholar] 113.Margulies K.B., Hernandez A.F., Redfield M.M., Givertz M.M., Oliveira G.H., Cole R

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Purifications were conducted by preparative RP-HPLC, eluting with a linear gradient (20 ml min 1 ) and using a binary solvent system consisting of H 2 O:MeCN:TFA (buffer A, 95:5:0.1

Rather than a fixed target, patients should monitor urine color (pale yellow indicates adequate hydration) and drink according to thirst, with increased intake during hot weather or physical activity

One common mistake is stopping during the worst of the adjustment period, usually around days five through seven, and then restarting a week later

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