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Staying hydrated can help regulate bowel movements and reduce discomfort

This helps reduce hunger, increase feelings of fullness, and decrease cravings

Refrigerate at 28C for optimal stability

That said, bioidentical compounded HRT specifically carries additional safety considerations that are worth discussing with a licensed clinician before starting

The trial itself explicitly concluded that while the drug showed promise, further studies were necessary to establish whether setmelanotide could elicit clinically meaningful weight loss in a subset of the MC4R -deficient obese population

However, it comes with a high cost, often exceeding $1,000 without insurance