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Obesity is Associated With Increased Risk of Crohns disease, but not Ulcerative Colitis: A Pooled Analysis of Five Prospective Cohort Studies

The dual GIP/GLP-1 mechanism of tirzepatide versus semaglutide does not guarantee worse digestive effects for every individual, even though the population-level data suggests slightly higher incidence

Clinical Research Overview Research examining GLP-1 medications shows that they can be effective tools for supporting weight loss and improving metabolic health

At Pharmacy M in Mexborough, our clinical team is committed to providing clear, transparent, and evidence-based guidance to help local patients navigate these choices safely and effectively

Specifically, a meta-analysis of the ELIXA, LEADER, SUSTAIN-6, EXSCEL, REWIND and AMPLITUDE-O trials in type 2 diabetes estimated a 21% reduction in the risk of new-onset macroalbuminuria, eGFR decline, progression to ESKD or death attributable to kidney causes with GLP1-RAs compared with placebo [48]