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GLP-1 receptors are located in brain reward regions including the ventral tegmental area and nucleus accumbens

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Magnesium glycinate (200 to 400 mg daily), B12 or methylcobalamin, vitamin D3 (2,000 to 4,000 IU daily), and a comprehensive electrolyte supplement are the most impactful

Higher cortisol levels are also associated with increased appetite and greater physiologic stress signaling in the body

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