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Preserving transcriptional stress responses as an anti-aging strategy

For medical affairs professionals, understanding these differences is critical to delivering ethical, compliant messaging

The MHRA update also complements the recent consensus statement from anaesthetic and specialist organisations that provides guidance for how the increased risk can be managed safely in the perioperative period. In early January 2025, the Association of Anaesthetists published a multidisciplinary consensus statement on elective peri-operative management of adults taking GLP-1 and dual GIP/GLP-1 RAs, which advised that patients take GLP-1 or dual GIP/GLP-1 RAs as normal, as well as receive a full risk assessment and peri-operative techniques to mitigate risk of pulmonary aspiration during the peri-operative period

Notably, none of the included trials investigated newer GLP-1 compounds such as tirzepatide, a dual GIP/GLP-1 receptor agonist, or semaglutide

Notably, most available studies lack direct assessments of muscle strength, physical performance, or gait speed

Is semaglutide the same as tirzepatide