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Retatrutides glucagon component appears particularly adept at addressing hepatic steatosis (fatty liver)

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Among the mechanisms, our research group and others have demonstrated that the gut microbiota fermentation (i.e., bacterial digestion of specific compounds) of specific prebiotics or other non-digestible carbohydrates is associated with the secretion of enteroendocrine peptides, such as the glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), produced by L-cells

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Some viewers questioned whether the side effects outweighed the benefits, and others expressed discomfort with celebrity endorsements in a medical context