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Yes weight regain after stopping is well-documented for both drugs

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Furthermore, a meta-analysis of data from large cardiovascular outcome trials (CVOT) demonstrates that GLP-1RA therapy does not seem to elevate the risk of pancreatic cancer in patients with T2DM [7]

Report Severe Reactions: If you notice significant redness, swelling, or pain, inform your healthcare provider

Naltrexone-bupropion (Contrave) combines an opioid blocker with an antidepressant to help control appetite and may work better for emotional or reward-based eating, says Rao

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