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Napoli R, Avogaro A, Formoso G, Piro S, Purrello F, Targher G, Consoli A

You do not get the metabolic upside without the rest of the glucagon signature coming along

However, several limitations were associated with these studies, including selection and recall bias, lack of interview bias, and the use of small sample sizes

In the ADRM1 high expression group, the expression of PD-L1 and PD-1 was increased, and patients with high ADRM1 expression were more likely to benefit from anti-PD-L1 therapy, with significantly higher proportions of CD8 + T cells and M1 macrophages, and significantly lower proportions of CD4 + T memory cells and mast cells, and higher TMB scores with a higher stemness index
