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Nevertheless, SGLT-1 versus SGLT-2 selectivity might have had an impact on the results of stroke prevention, and this effect may have contributed to the discrepancy between pairwise meta-analysis and network meta-analysis

The effect was dose-dependent

It also reduces the release of glucagon, which causes the liver to release too much glucose

When a medication comes off patent, cheaper generics/biosimilars tend to come to market

Start with a foundational multivitamin and protein source, then add targeted supplements (omega-3, extra iron, vitamin D) only if bloodwork or symptoms indicate a gap

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