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Evidence now warrants a focus on the beta cell itself and how to avoid its dysfunction, which is putatively caused by cytokine-driven inflammation and other stress factors, leading to low insulin-secretory capacity, autoantigen presentation and immune-mediated destruction

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In the US, Novo is protected until 2031 through patent term extensions, so the bifurcation between a commodity market in Asia and a premium market in the West is the defining dynamic for the next five years

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