should you stop tirzepatide before surgery Surgery: Safe Pause, Smart Recovery 📌 DRUGS TO STOP BEFORE

This is currently being investigated in a phase 2 clinical trial (127)

H., Urva, S., et al

This results in a lower ability to promote receptor internalization compared with endogenous GLP-1, so it allows to have an increased GLP-1R expression on the cell surface, which translates in more robust insulinotropic properties, possibly explaining the enhanced insulin secretion (in both diabetic and not diabetic human islets), induced by TZP (48) ( Figure 1 )

Know the difference

FIGURE 9 3.4 Tirzepatide vs semaglutide 3.4.1 Study characteristics This section undertook a comprehensive examination of two RCT studies

References: GLP-1 Benefit Coverage | Aetna