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Gastrointestinal adverse reactions, including diarrhea, were the most common reason for treatment discontinuation in clinical trials, with approximately 4-7% of patients discontinuing due to GI events

Clinical evidence gap Injectable tirzepatide has been studied in tens of thousands of participants across multiple phase 3 clinical trials

Quick Answer: Current evidence does not establish a causal link between tirzepatide and memory problems, and clinical trials have not identified cognitive impairment as a significant adverse event

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You could clearly see that [patients] had no clinical benefit whatsoever. Sometimes when clinical trials offer disappointing results, she says, people question whether there were problems with the studys design

Retrieved from Williams, E., Rudowitz, R., & Bell, C