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Quick Answer: GLP-1 medications cause headaches primarily through dehydration from gastrointestinal side effects, blood glucose fluctuations, and metabolic changes during treatment

Individuals using GLP-1RAs lose around 2050 % of lean body mass, which is much higher than weight loss through traditional diet and exercise [50]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Hlscher C

It can decrease your resting metabolic rate, meaning your body burns fewer calories when you're at rest

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