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Results CNR1 expression was upregulated in circulating CD4+ T cells from individuals at type 1 diabetes onset (6.9-fold higher vs healthy individuals) and in sorted islet beta cells from donors with type 1 diabetes (3.6-fold higher vs healthy counterparts)

14 mg in individuals with type 2 diabetes and overweight/obesity: Increasing the expectations to the efficacy of oral semaglutide 50 mg once daily in obesity without type 2 diabetes (for some currently unclear reason(s), body weight-lowering medications tend to have smaller effects in people with type 2 diabetes)

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