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Patients and physicians have reported severe gastrointestinal complications involving persistent vomiting, severe nausea, abdominal pain, dehydration, malnutrition, and delayed stomach emptying that, in some cases, required hospitalization or emergency room treatment

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A baseline ultrasound is not required for all patients but is strongly recommended for those with existing risk factors: women over 40, family history of gallstones, BMI over 40, Hispanic or Native American ethnicity, or history of gallbladder symptoms