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Moreover, our analysis of seven patients from the combined therapy group suggests that GLP-1 agonists allow for a reduction in acetazolamide dosage in the treatment of IIH without changing the clinical outcome.

There's also data suggesting that in some cases, people who take GLP-1s for several years can start to experience a waning effect - perhaps a drug resistance - where they start to regain some weight, even while taking the medication

Evidence-based guidance on tolerability, practical strategies to reduce nausea, and when to seek medical advice for GLP-1 receptor agonist therapy.

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