glp-1 agonist medications New Guidelines for Type 2 Diabetes in 2025 The ABC's of GLP-1s: Benefits,

Even without concurrent medications, unexplained hypoglycemia symptoms should be reported and investigated

While insulin lowers blood glucose, glucagon raises it by signaling the liver to release stored sugar into the bloodstream

Manufacturing capacity expansion by Novo Nordisk and Eli Lilly with billions in active peptide production facility investment is working to resolve supply shortages that have limited GLP-1 market penetration despite strong prescription demand

Dubrows guide to GLP-1sand why retatrutide could change the game Retatrutide has the most buzz, but it will be impossible to get a legal prescription for the weekly injectable for at least several months, as the final phase of testing is being analyzed and must still be sent to the FDA for approval

Ct and colleagues highlight the concern that GLP-1 RAs treatment could exacerbate social stigmatization or prompt feelings of shame if weight rebounds after stopping therapy (43)

The Bottom Line GLP-1 drugs have real benefits, but the risks are becoming harder to ignore