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This means comparing Patchie to prescription GLP-1 medications is not an apples-to-apples comparison
The result can be worse than where they started: the return of prediabetes, hypertension, dyslipidemia, and weight regain, sometimes compounded by muscle loss that leaves them in poorer overall health

[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Bagga P., Hariharan H., Wilson N.E., Beer J.C., Shinohara R.T., Elliott M.A., Baur J.A., Marincola F.M., Witschey W.R., Haris M., et al
Too much high-intensity work while your body is readjusting to life without tirzepatide can increase cortisol, which promotes fat storage, particularly around the midsection

After 10 years of treatment, the incidence of MALE was significantly lower in the GLP-1RAs group than in the non-GLP-1RAs group (Monfeuga et al., 2024)

Estrogenic control of mitochondrial function
