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Ertugliflozin (Steglatro, Merck) Indication and Clinical Profile 1,2 : Ertugliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that has been approved for the treatment of type 2 diabetes (DM2) in adult patients as an adjunct to diet and exercise

The complexity of the immuneendocrine axis is further highlighted by the unexpected finding that mice overexpressing TNF are protected from high-fat diet-induced insulin resistance (207)

Clinical trials, like the ACRC Trials Weight Loss Study, are being conducted to carefully test these new approaches and monitor their safety

Readers can verify the current status, naming, and scope of these trials via ClinicalTrials.gov, where registered study records and NCT identifiers are publicly available

Eligibility depends on state participation and clinical criteria