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Shaefer CF, Kushner P, Aguilar R

In addition, variants linked to both GLP1R and GIPR are associated with GLP1 medication-related nausea and vomiting

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Their primary indication is the management of type 2 diabetes, where they are used alongside diet and exercise to improve glycaemic control by enhancing insulin secretion, suppressing glucagon, and supporting healthier glucose regulation 3 , 4

332,333,334 The NO produced by iNOS, as a free radical, can regulate intracellular signal transduction and modulate the inflammatory response

Long-chain fatty acids, particularly omega-3s and monounsaturated fats, trigger L-cell activation through GPR120 and GPR40 receptors
