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Based on accumulated evidence, it does not seem like GLP-1 drugs when used during the months after conception increase the risk of common (adverse) outcomes substantially

Insulin-like growth factor binding protein 2 null mice ( Igfbp2-/- ) are protected against trabecular bone loss after vertical sleeve gastrectomy

doi: 10.17925/ee.2019.15.2.83 35 WangBZhongJLinHZhaoZYanZHeHet al

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Improved Insulin Sensitivity: Tirzepatide enhances insulin sensitivity in peripheral tissues, allowing more efficient glucose uptake and utilization, particularly beneficial for individuals with insulin resistance, a hallmark of type 2 diabetes