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Here, we show that the long-acting GLP-1R agonist semaglutide (SG) suppresses voluntary wheel running in both lean and diet-induced obese mice

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Elevated dopamine transporter density may be a consequence of chronic treatment rather than a marker for the disorder and may have implications for the effectiveness of long-term treatment.

It's a question physicians are being asked regularly these days.

National Institutes of Health (NIH) PMC Medical Library on Semaglutide Long-Term Maintenance Outcomes, Chronic Weight Control Studies, Gastric Clearing Rates, and Advanced Metabolic Reconditioning