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The primary endpoint was percent change in body weight from randomization (week 36) to the end of the trial (week 88)

These hormones play crucial roles in regulating appetite, food intake, and how your body processes glucose

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The published case literature supports this, showing that most patients who continued tirzepatide through mild to moderate injection site reactions experienced gradual improvement without needing to discontinue

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The drug is now also approved for obstructive sleep apnea in adults with obesity, where it cut the apnea-hypopnea index by about half in the SURMOUNT-OSA trial
