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Tirzepatide is a novel agent that acts as an agonist for both GLP-1 receptors and gastric inhibitory polypeptide (GIP) receptors, another incretin that lowers glucose and appetite

Exenatide (Ex-4) and liraglutide are effective in modulating key pathways involved in neurodegeneration, such as apoptosis, mitochondrial function, and autophagy, in models of AD and PD

[DOI] [PubMed] [Google Scholar] 12.M

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Severe restriction accelerates muscle loss and is unsustainable it makes the plateau worse, not better

[DOI] [PubMed] [Google Scholar] 18.Meloni A.R., DeYoung M.B., Lowe C., Parkes D.G