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23 In clinical trials, treatment-discontinuation rates are around 5% to 10%

Sound mechanistic evidence supports the need for further research on the GLP1-RAs/SGLT2is combinations ability to modify specific risk outcomes, such as cardiovascular risk and the progression of diabetic kidney disease
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FDA-approved GLP-1 medications for weight management are indicated for adults with a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related health condition

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article

Others indicate you may need higher tirzepatide doses to see results

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