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[16] in 2013 demonstrated that the use of topical carbonic anhydrase inhibitors (CAI), such as dorzolamide (Trusopt ) and brinzolamide (Azopt ), may be safe in patients who report a history of sulfa allergy

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Their effectiveness has revolutionized diabetes care, and brands like Ozempic and Mounjaro have become household names

Common side effects include headaches, flushing, indigestion, nasal congestion, dizziness, and vision changes such as seeing a blue tinge to objects or having difficulty distinguishing between blue and green

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Methacholine is an acetylcholine receptor agonist