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If metformin becomes difficult to tolerate due to semaglutide-induced nausea, your doctor may temporarily reduce the metformin dose or switch to a modified-release formulation that is gentler on the stomach

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Efectos secundarios persistentes o graves : Aunque los efectos gastrointestinales leves son comunes al inicio del tratamiento, debe buscar atencin mdica si experimenta: Nuseas o vmitos severos que impiden la ingesta adecuada de alimentos o lquidos Dolor abdominal intenso y persistente, especialmente si se irradia a la espalda (posible pancreatitis) Dolor en el cuadrante superior derecho del abdomen, ictericia o fiebre (posible problema de vescula biliar) Signos de deshidratacin debido a vmitos o diarrea prolongados (que pueden aumentar el riesgo de lesin renal aguda) Cambios visuales o sntomas de retinopata diabtica Sntomas de hipoglucemia (mareos, sudoracin, confusin), especialmente si toma insulina o sulfonilureas concomitantemente Reacciones alrgicas graves como hinchazn facial o dificultad para respirar Situaciones especiales : Consulte inmediatamente con su mdico si est embarazada, planea quedar embarazada o est amamantando, ya que estos medicamentos no estn recomendados durante el embarazo o lactancia y deben suspenderse con anticipacin segn su vida media
However, if the rash spreads beyond the injection site, persists beyond one week, or you develop systemic symptoms, stop further doses and contact your GP or diabetes specialist before the next injection
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