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Key Takeaways Retatrutide and tirzepatide target different combinations of metabolic receptors, influencing their effects on weight loss and glucose control
MuRF1 targets structural proteins such as myosin heavy chain and troponin, while Atrogin-1 promotes degradation of proteins involved in muscle growth and regeneration, including MyoD and eIF3f [99, 100]
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In mammals, the Foxo subfamily is comprised of four members: Foxo1, Foxo3, Foxo4, and Foxo6
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