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GLP-1RAs (e.g., exenatide and liraglutide) appear effective in modulating BAT thermogenesis and browning, controlling food intake, and increasing energy expenditure through the action on the hypothalamic AMPK pathway, with clinically significant effects

Chronic stress, anxiety, and depression profoundly affect cognitive function

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Shift to a quarterly schedule that includes professional cleaning, caries risk assessment, and salivary flow evaluation