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The trial demonstrated that semaglutide significantly reduced the risk of a major kidney event, including kidney failure, a 50% or greater reduction in estimated glomerular filtration rate (eGFR), or death from kidney-related or cardiovascular causes, in patients with CKD and Type 2 diabetes

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However, ELISA analysis showed that serum GLP-1 levels were similar in normal controls and NAFLD patients (Fig

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Others failed to properly monitor patients for signs of severe gastrointestinal injuries, pancreatitis, or vision loss

Results vary among studies, highlighting the need for further research to fully clarify the extent of this association and provide clearer indications of clinical implications