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Importantly, efpeglenatides immunogenicity remained relatively low, with few patients developing clinically significant anti-drug antibodies, allowing its safety profile to be viewed as manageable within class expectations

This pathway has been beautifully illustrated by Krajnc et al
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Neuschwander-Tetri, B

Long-term use is required to maintain weight loss, and when people stop taking them it usually results in weight regain

doi: 10.1016/0014-5793(89)80899-3

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