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When taking into consideration all malignant disease categories together (including pancreatic carcinoma and thyroid cancer), the analysis demonstrated not an overall increase in the odds ratio for all malignant disease but, rather, a trend toward a reduction, especially with sitagliptin treatment ( P = 0.068

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However, the strength of TRIUMPH-4 data and the commercial incentive for Eli Lilly make significant delays unlikely barring an unexpected safety finding

Evolution of Longer-Acting Formulations Once the chemistry was established, the next mission scientists faced was to make GLP-1 agonists last longer in the body, so patients wouldnt have to keep poking themselves like a pincushion